Impact of vitamin D and vitamin D receptor on the trophoblast survival capacity in preeclampsia

The effect of vitamin D supplementation on the size of uterine leiomyoma in women with vitamin D deficiency

Vitamin D, vitamin D receptor and tissue barriers

Tissue barriers are critical in the pathogenesis of human diseases, such as atopic dermatitis, inflammatory bowel diseases, and various cancers. Preserving or restoring barrier functions of the epithelia cells is a therapeutic strategy to prevent and treat the illness. Mounting evidence indicates that vitamin D and the vitamin D receptor (VDR) play key roles in the pathogenesis of human disease...

The Relationship of Vitamin D and Calcium level with Preeclampsia Severity: A Case- control Study

Background Vitamin D deficiency is associated with physiologic changes that are similar to pathogenesis of preeclampsia. Although association of vitamin D and preeclampsia has been studied previously, their results are not consistent. The aim of this study was to investigate the relationship of serum vitamin D and calcium with preeclampsia severity. Materials and Methods: This case- control st...

Active vitamin D and survival.

Vitamin D is more than just a therapeutic tool for lowering elevated levels of parathyroid hormone (PTH) in patients on dialysis. Deficiencies in the vitamin D axis cause osteomalacia, rickets, and myopathy and are associated with a variety of extraskeletal problems, including cardiovascular disease, infection, malignancy, and death.1,2 Interestingly, the growing awareness of a potential link a...

The trophoblast survival capacity in preeclampsia

BACKGROUND Preeclampsia has become the world's major maternal health problem putting a huge burden on mothers, newborns and also on the health systems. The pathogenesis of preeclampsia seems to include events in very early pregnancy affecting differentiation of placental villous trophoblast. The arising changes of the cell death spectrum from apoptosis via increased autophagy and aponecrosis to...